USE OF THE CARBOPALLADATION OF 1,2-PROPADIENE IN A 2 STEP SYNTHESIS OF STEROIDS

被引：23

作者：

GAUTHIER, V

CAZES, B

GORE, J

机构：

[1] Laboratoire de Chimie Organique I, associé au CNRS, Université Claude Bernard, 69622 Villeurbanne, 43 Bd du

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 07期

关键词：

D O I：

10.1016/S0040-4039(00)92119-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The palladium-catalyzed reaction of 1,2-propadiene, the enol triflate of an alpha-tetralone and the enolate of 2-methyl-1,3-cyclopentanedione leads to compounds such as 1a which are transformed under acidic conditions to steroidal trienones. This approach to the steroid skeleton is presently limited to compounds having an aromatic A-ring.

引用

页码：915 / 918

页数：4

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