Strategies for reducing body fat mass: effects of liposuction and exercise on cardiovascular risk factors and adiposity

被引:23
作者
Benatti, Fabiana Braga [1 ]
Lira, Fabio Santos [2 ]
Oyama, Lila Missae [2 ]
da Penha Oller do Nascimento, Cludia Maria [2 ]
Lancha Junior, Antonio Herbert [1 ]
机构
[1] Univ Sao Paulo, Sch Phys Educ & Sport, Sao Paulo, Brazil
[2] Univ Fed Sao Paulo, Dept Physiol, Div Nutr Physiol, Sao Paulo, Brazil
关键词
adipose tissue; inflammatory markers; exercise; insulin; metabolism;
D O I
10.2147/DMSO.S12143
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Liposuction is the most popular aesthetic surgery performed in Brazil and worldwide. Evidence showing that adipose tissue is a metabolically active tissue has led to the suggestion that liposuction could be a viable method for improving metabolic profile through the immediate loss of adipose tissue. However, the immediate liposuction-induced increase in the proportion of visceral to subcutaneous adipose tissue could be detrimental to metabolism, because a high proportion of visceral to subcutaneous adipose tissue is associated with risk factors for cardiovascular disease. The results of studies investigating the effects of liposuction on the metabolic profile are inconsistent, however, with most studies reporting either no change or improvements in one or more cardiovascular risk factors. In addition, animal studies have demonstrated a compensatory growth of intact adipose tissue in response to lipectomy, although studies with humans have reported inconsistent results. Exercise training improves insulin sensitivity, inflammatory balance, lipid oxidation, and adipose tissue distribution; increases or preserves the fat-free mass; and increases total energy expenditure. Thus, liposuction and exercise appear to directly affect metabolism in similar ways, which suggests a possible interaction between these two strategies. To our knowledge, no studies have reported the associated effects of liposuction and exercise in humans. Nonetheless, one could suggest that exercise training associated with liposuction could attenuate or even block the possible compensatory fat deposition in intact depots or regrowth of the fat mass and exert an additive or even a synergistic effect to liposuction on improving insulin sensitivity and the inflammatory balance, resulting in an improvement of cardiovascular risk factors. Consequently, one could suggest that liposuction and exercise appear to be safe and effective strategies for either the treatment of metabolic disorders or aesthetic purposes.
引用
收藏
页码:141 / 154
页数:14
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