Neuropsychiatric Symptoms as The First Manifestation of Juvenile Systemic Lupus Erythematosus: A Complicated Case with Klinefelter's Syndrome

被引:0
作者
Shiari, Reza [1 ]
Hassase Yegane, Mehrnoush [1 ]
Farivar, Shirin [2 ]
Javadi Parvaneh, Vadood [1 ]
Mirjavadi, Seyed Alireza [1 ]
机构
[1] Shahid Behshti Univ Med Sci, Dept Paediat Rheumatol, Mofid Childrens Hosp, Tehran, Iran
[2] Shahid Beheshti Univ, Fac Biol Sci, Dept Genet, GC, Tehran, Iran
关键词
Juvenile Systemic Lupus Erythematosus; Klinefelter's syndrome; Cognitive Dysfunction; Neuropsychiatric;
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Systemic Lupus Erythematosus (SLE) is an autoimmune, multisystem disorder with various manifestations. There are limited reports on the neuropsychiatric findings as the first manifestation of SLE in children. Herein, we report a 14-year-old Iranian boy with a two-year history of cognitive dysfunction and behavioural problems as well as a recent history of epistaxis. The patient workup ended with a diagnosis of Klinefelter's syndrome associated with juvenile SLE. Patients with Klinefelter's syndrome may exhibit behavioural problems and psychological disease. These psychiatric disorders could be complicated with lupus in children. In fact, psychiatric symptoms may occur as the first manifestation of juvenile SLE. Specially, if accompanied with Klinefelter's syndrome. We suggest the diagnosis of SLE must be considered in all children with neuropsychiatric manifestations.
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页码:62 / 65
页数:4
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