HOMOZYGOUS C3 DEFICIENCY ASSOCIATED WITH IGA NEPHROPATHY

被引：20

作者：

IMAI, K ^{[1
]}

NAKAJIMA, K ^{[1
]}

EGUCHI, K ^{[1
]}

MIYAZAKI, M ^{[1
]}

ENDOH, M ^{[1
]}

TOMINO, Y ^{[1
]}

NOMOTO, Y ^{[1
]}

SAKAI, H ^{[1
]}

HYODO, Y ^{[1
]}

机构：

[1] KANAGAWA CHILDRENS MED CTR,DEPT INFECT & IMMUNOL,YOKOHAMA,KANAGAWA,JAPAN

来源：

NEPHRON | 1991年 / 59卷 / 01期

关键词：

C3; DEFICIENCY; IGA NEPHROPATHY;

D O I：

10.1159/000186535

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

A 23-year-old male patient with homozygous C3 deficiency who developed asymptomatic proteinuria and hematuria was reported. Renal biopsy disclosed typical IgA nephropathy with deposition of early- and late-complement components except for C3 deposition. C9 and membrane attack complex were detected in the glomeruli despite the absence of C3. It was suggested that there might be some unknown complement activation mechanism which does not require C3 component.

引用

页码：148 / 152

页数：5

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