6-DEOXYACYCLOVIR - A XANTHINE OXIDASE-ACTIVATED PRODRUG OF ACYCLOVIR

被引：153

作者：

KRENITSKY, TA ^{[1
]}

HALL, WW ^{[1
]}

DEMIRANDA, P ^{[1
]}

BEAUCHAMP, LM ^{[1
]}

SCHAEFFER, HJ ^{[1
]}

WHITEMAN, PD ^{[1
]}

机构：

[1] WELLCOME RES LABS, BECKENHAM BR3 3BS, KENT, ENGLAND

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES | 1984年 / 81卷 / 10期

关键词：

D O I：

10.1073/pnas.81.10.3209

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：3209 / 3213

页数：5

共 25 条

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[4] TREATMENT OF 1ST EPISODES OF GENITAL HERPES-SIMPLEX VIRUS-INFECTION WITH ORAL ACYCLOVIR - A RANDOMIZED DOUBLE-BLIND CONTROLLED TRIAL IN NORMAL SUBJECTS
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[5] SYNTHESIS AND ANTIVIRAL ACTIVITY OF WATER-SOLUBLE ESTERS OF ACYCLOVIR [9-[(2-HYDROXYETHOXY)METHYL]GUANINE]
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[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1983, 26 (04) : 602 - 604
[6] DOUBLE-BLIND CONTROLLED TRIAL OF TOPICAL ACYCLOVIR IN GENITAL HERPES-SIMPLEX VIRUS-INFECTIONS
COREY, L
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CRITCHLOW, CW
REMINGTON, MR
WINTER, CA
FAHNLANDER, AL
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[J]. AMERICAN JOURNAL OF MEDICINE, 1982, 73 (1A) : 326 - 334
[7] INTRAVENOUS ACYCLOVIR FOR THE TREATMENT OF PRIMARY GENITAL HERPES
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FIFE, KH
BENEDETTI, JK
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FAHNLANDER, A
CONNOR, JD
HINTZ, MA
HOLMES, KK
[J]. ANNALS OF INTERNAL MEDICINE, 1983, 98 (06) : 914 - 921
[8] A TRIAL OF TOPICAL ACYCLOVIR IN GENITAL HERPES-SIMPLEX VIRUS-INFECTIONS
COREY, L
NAHMIAS, AJ
GUINAN, ME
BENEDETTI, JK
CRITCHLOW, CW
HOLMES, KK
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1982, 306 (22) : 1313 - 1319
[9] PHARMACOKINETICS OF ACYCLOVIR AFTER INTRAVENOUS AND ORAL-ADMINISTRATION
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BLUM, MR
[J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1983, 12 : 29 - 37
[10] DEMIRANDA P, 1981, J PHARMACOL EXP THER, V219, P309

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