SIMULATION AND ANALYSIS BY DIGITAL COMPUTER OF BIOCHEMICAL SYSTEMS IN TERMS OF KINETIC MODELS .4. AUTOMATIC DERIVATION OF ENZYMIC RATE LAWS

被引：19

作者：

RHOADS, DG

PRING, M

机构：

[1] Graduate Department of Biochemistry, Brandeis University, Waltham

[2] Balliol College, Oxford, England

来源：

JOURNAL OF THEORETICAL BIOLOGY | 1968年 / 20卷 / 03期

关键词：

D O I：

10.1016/0022-5193(68)90130-6

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The application of the steady-state assumption to the enzyme species in kinetic models of biochemical systems is described. A set of rules for the derivation of the rate laws of complex enzymes under this assumption is available (King & Altman, 1956). Two programmes, which carry out a symbolic derivation of this kind, and can be used as part of a generator system for simulation by this method, are described in detail. The limitations and advantages of this approach are discussed. © 1968.

引用

页码：297 / &

共 5 条

[1] A note on the kinetics of enzyme action. [J].