CONTROL OF SELECTIVITY IN MICELLAR ELECTROKINETIC CHROMATOGRAPHY BY MODIFICATION OF SODIUM DODECYL-SULFATE MICELLES WITH ORGANIC HYDROXY COMPOUNDS

被引：23

作者：

KATSUTA, S ^{[1
]}

TSUMURA, T ^{[1
]}

SAITOH, K ^{[1
]}

TERAMAE, N ^{[1
]}

机构：

[1] TOHOKU UNIV,FAC SCI,DEPT CHEM,SENDAI,MIYAGI 98077,JAPAN

来源：

JOURNAL OF CHROMATOGRAPHY A | 1995年 / 705卷 / 02期

基金：

日本学术振兴会;

关键词：

D O I：

10.1016/0021-9673(95)00291-T

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Modification of micellar phases with solubilized solutes was examined to control the separation in micellar electrokinetic chromatography (MEKC). The addition of organic hydroxy compounds (1-hexanol, cyclohexanol and phenol) as modifiers to a micellar solution of sodium dodecyl sulfate specifically decreased the capacity factor of some aromatic analytes possessing hydrophilic functional groups. The effect of phenol was different in selectivity to that of 1-hexanol and cyclohexanol. The effects of these modifiers were mainly explained in terms of the saturation of the micellar palisade layer with the modifiers and the hydrogen-bond interaction between the modifier and analyte molecules in the micellar phase. Such micellar modification were applied to improve the MEKC separation.

引用

页码：319 / 324

页数：6

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