WHITE-MATTER HYPERINTENSITY SIGNALS ASSOCIATED WITH VASCULAR RISK-FACTORS IN SCHIZOPHRENIA

被引：11
作者：
BROWN, FW
LEWINE, RRJ
HUDGINS, PA
机构：
[1] EMORY UNIV, SCH MED, DEPT PSYCHIAT & BEHAV SCI, ATLANTA, GA USA
[2] EMORY UNIV, SCH MED, DEPT NEURORADIOL, ATLANTA, GA USA
来源：
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY | 1995年 / 19卷 / 01期
关键词：
HYPERTENSION; MAGNETIC RESONANCE IMAGING; SCHIZOPHRENIA; VASCULAR; WHITE MATTER HYPERINTENSITY SIGNALS;
D O I：
10.1016/0278-5846(94)00102-N
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
1. A sample of 165 schizophrenic subjects was compared to a normal control group in order to evaluate associations between white matter hyperintensity signals and vascular risk factors. 2. A comprehensive medical chart review was completed on all. subjects evaluating potential vascular risk factors. Brain MRI acquisition was performed with 0.5 and 1.5 Telsa Philips scanners. 3. Prevalence rates of WMH signals in schizophrenic subjects and normal controls were 4.8% and 4.9%, respectively. 4. A significant association was found for schizophrenics with WMH signals to schizophrenics without signals for hypertension and history of CVA's. 5. This finding is consistent with an etiology of WMH signals in schizophrenia being related to vascular disease.
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页码：39 / 45
页数：7
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