NEUTROPHIL-MEDIATED INJURY TO ENDOTHELIAL-CELLS - ENHANCEMENT BY ENDOTOXIN AND ESSENTIAL ROLE OF NEUTROPHIL ELASTASE

被引：599
作者：
SMEDLY, LA
TONNESEN, MG
SANDHAUS, RA
HASLETT, C
GUTHRIE, LA
JOHNSTON, RB
HENSON, PM
WORTHEN, GS
机构：
[1] NATL JEWISH CTR IMMUNOL & RESP MED, DEPT PEDIAT, DENVER, CO 80206 USA
[2] VET ADM MED CTR, DENVER, CO 80220 USA
[3] UNIV COLORADO, SCH MED, DEPT MED, DENVER, CO 80206 USA
[4] UNIV COLORADO, SCH MED, DEPT PEDIAT, DENVER, CO 80206 USA
[5] UNIV COLORADO, SCH MED, DEPT PATHOL, DENVER, CO 80206 USA
[6] UNIV COLORADO, SCH MED, DEPT DERMATOL, DENVER, CO 80206 USA
[7] NATL JEWISH CTR IMMUNOL & RESP MED, DEPT MED, DENVER, CO 80206 USA
来源：
JOURNAL OF CLINICAL INVESTIGATION | 1986年 / 77卷 / 04期
关键词：
D O I：
10.1172/JCI112426
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
引用
收藏
页码：1233 / 1243
页数：11
相关论文
共 59 条
[1]  
ALTMAN PL, 1977, HUMAN HLTH DISEASE, V2, P212
[2]   LACTOFERRIN ENHANCES HYDROXYL RADICAL PRODUCTION BY HUMAN-NEUTROPHILS, NEUTROPHIL PARTICULATE FRACTIONS, AND AN ENZYMATIC GENERATING-SYSTEM [J].
AMBRUSO, DR ;
JOHNSTON, RB .
JOURNAL OF CLINICAL INVESTIGATION, 1981, 67 (02) :352-360
[3]   SENSITIVE METHOD FOR THE ESTIMATION OF HYDROGEN PEROXIDE IN BIOLOGICAL MATERIALS [J].
ANDREAE, WA .
NATURE, 1955, 175 (4463) :859-860
[4]  
BACHOFEN M, 1982, CLIN CHEST MED, V3, P35
[5]   REGULATION OF ALPHA-1 PROTEINASE-INHIBITOR FUNCTION BY RABBIT ALVEOLAR MACROPHAGES - EVIDENCE FOR PROTEOLYTIC RATHER THAN OXIDATIVE INACTIVATION [J].
BANDA, MJ ;
CLARK, EJ ;
WERB, Z .
JOURNAL OF CLINICAL INVESTIGATION, 1985, 75 (06) :1758-1762
[6]   HUMAN LEUKOCYTE GRANULE ELASTASE - RAPID ISOLATION AND CHARACTERIZATION [J].
BAUGH, RJ ;
TRAVIS, J .
BIOCHEMISTRY, 1976, 15 (04) :836-841
[7]   INCREASED SHEEP LUNG VASCULAR-PERMEABILITY CAUSED BY PSEUDOMONAS BACTEREMIA [J].
BRIGHAM, KL ;
WOOLVERTON, WC ;
BLAKE, LH ;
STAUB, NC .
JOURNAL OF CLINICAL INVESTIGATION, 1974, 54 (04) :792-804
[8]   GRANULOCYTE-DEPENDENT INJURY OF PULMONARY ENDOTHELIUM - A CASE OF MISCOMMUNICATION [J].
BRIGHAM, KL ;
MEYRICK, B .
TISSUE & CELL, 1984, 16 (02) :137-155
[9]   PROTEOLYSIS BY NEUTROPHILS - RELATIVE IMPORTANCE OF CELL-SUBSTRATE CONTACT AND OXIDATIVE INACTIVATION OF PROTEINASE-INHIBITORS INVITRO [J].
CAMPBELL, EJ ;
SENIOR, RM ;
MCDONALD, JA ;
COX, DL .
JOURNAL OF CLINICAL INVESTIGATION, 1982, 70 (04) :845-852
[10]   POTENTIAL MEDIATOR OF INFLAMMATION - PHAGOCYTE-DERIVED OXIDANTS SUPPRESS THE ELASTASE-INHIBITORY CAPACITY OF ALPHA1-PROTEINASE INHIBITOR INVITRO [J].
CARP, H ;
JANOFF, A .
JOURNAL OF CLINICAL INVESTIGATION, 1980, 66 (05) :987-995
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