THE XENOPUS YB3-PROTEIN BINDS THE B-BOX ELEMENT OF THE CLASS-III PROMOTER

被引：28

作者：

COHEN, I ^{[1
]}

REYNOLDS, WF ^{[1
]}

机构：

[1] LA JOLLA CANC RES FDN,10901 N TORREY PINES RD,LA JOLLA,CA 92037

来源：

NUCLEIC ACIDS RESEARCH | 1991年 / 19卷 / 17期

关键词：

D O I：

10.1093/nar/19.17.4753

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have isolated a Xenopus cDNA encoding the YB3 protein which binds specifically to the B box promoter element of class III genes. Northern analysis shows YB3 is expressed in a variety of adult tissues. Fractionation of oocyte S150 extracts demonstrates YB3 is present in phosphocellulose fraction IIIC, as well as in the fraction isolated by B box DNA affinity chromatography. Silver staining indicates that YB3, or a protein of the same mobility in SDS gels, is the most abundant component in either fraction.

引用

页码：4753 / 4759

页数：7

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