A MECHANISTIC BASIS FOR THE STEREOSELECTIVITY OF ENZYMATIC TRANSFER OF HYDROGEN FROM NICOTINAMIDE COFACTORS

被引：136

作者：

NAMBIAR, KP ^{[1
]}

STAUFFER, DM ^{[1
]}

KOLODZIEJ, PA ^{[1
]}

BENNER, SA ^{[1
]}

机构：

[1] HARVARD UNIV, DEPT CHEM, CAMBRIDGE, MA 02138 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1983年 / 105卷 / 18期

关键词：

D O I：

10.1021/ja00356a028

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：5886 / 5890

页数：5

共 31 条

[1] EFFICIENCY AND EVOLUTION OF ENZYME CATALYSIS [J].

ALBERY, WJ ;

KNOWLES, JR .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1977, 16 (05) :285-293

[2] EVOLUTION OF ENZYME FUNCTION AND DEVELOPMENT OF CATALYTIC EFFICIENCY [J].

ALBERY, WJ ;

KNOWLES, JR .

BIOCHEMISTRY, 1976, 15 (25) :5631-5640

[3] TENTATIVE CLASSIFICATION OF NAD(P)-LINKED DEHYDROGENASES IN REGARD TO THEIR STEREOCHEMISTRY OF HYDROGEN TRANSFER TO COENZYME [J].

ALIZADE, MA ;

BRENDEL, K .

NATURWISSENSCHAFTEN, 1975, 62 (07) :346-348

[4]

ALTONA C, 1959, TETRAHEDRON LETT, P16

[5]

[Anonymous], 1971, PURE APPL CHEM

[6] Oxidation potentials of ketones and an aldehyde [J].

Baker, RH ;

Adkins, H .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1940, 62 :3305-3314

[7] ANALOGS FOR ACETOACETATE AS AN ENZYME SUBSTRATE - STEREOCHEMICAL PREFERENCES [J].

BENNER, SA ;

MORTON, TH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1981, 103 (04) :991-993

[8] THE STEREOSELECTIVITY OF ALCOHOL DEHYDROGENASES - A STEREOCHEMICAL IMPERATIVE [J].

BENNER, SA .

EXPERIENTIA, 1982, 38 (05) :633-637

[9]

BENNER SA, 1982, CHEM APPROACHES UNDE

[10]

BENTLEY R, 1970, MOL ASYSMMETRY BIOL, V2

← 1 2 3 4 →