Two independent cross-over studies have now been carried out to evaluate the effect of a regime of chewing sucrose-containing gum on enamel lesion remineralization. The first study has been reported in detail elsewhere. This further study aimed to increase the data set with an additional 13 volunteers. Similar protocols were followed in both studies. Weighted averages from the two studies showed Delta z values corresponding to 16.8% remineralization for the gum versus 11.6% remineralization for the control (p = 0.046, two-sided). A significant difference between test and control was evident for lesion body (p = 0.0004, two-sided) but not for surface zone (p = 0.32, two-sided).
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Tokyo Med & Dent Univ, Dept Restorat Sci, Grad Sch Med & Dent Sci, Bunkyo Ku, Tokyo 1138549, JapanTokyo Med & Dent Univ, Dept Restorat Sci, Grad Sch Med & Dent Sci, Bunkyo Ku, Tokyo 1138549, Japan
Kitasako, Yuichi
Tanaka, Miyuki
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机构:Tokyo Med & Dent Univ, Dept Restorat Sci, Grad Sch Med & Dent Sci, Bunkyo Ku, Tokyo 1138549, Japan
Tanaka, Miyuki
Sadr, Alireza
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Tokyo Med & Dent Univ, Global Ctr Excellence Program, Int Res Ctr Mol Sci Tooth & Bone Dis, Grad Sch, Tokyo 1138549, JapanTokyo Med & Dent Univ, Dept Restorat Sci, Grad Sch Med & Dent Sci, Bunkyo Ku, Tokyo 1138549, Japan
Sadr, Alireza
Hamba, Hidenori
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Tokyo Med & Dent Univ, Global Ctr Excellence Program, Int Res Ctr Mol Sci Tooth & Bone Dis, Grad Sch, Tokyo 1138549, JapanTokyo Med & Dent Univ, Dept Restorat Sci, Grad Sch Med & Dent Sci, Bunkyo Ku, Tokyo 1138549, Japan
Hamba, Hidenori
Ikeda, Masaomi
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Tokyo Med & Dent Univ, Fac Dent, Sch Dent Technol, Tokyo 1138549, JapanTokyo Med & Dent Univ, Dept Restorat Sci, Grad Sch Med & Dent Sci, Bunkyo Ku, Tokyo 1138549, Japan
Ikeda, Masaomi
Tagami, Junji
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Tokyo Med & Dent Univ, Global Ctr Excellence Program, Int Res Ctr Mol Sci Tooth & Bone Dis, Grad Sch, Tokyo 1138549, JapanTokyo Med & Dent Univ, Dept Restorat Sci, Grad Sch Med & Dent Sci, Bunkyo Ku, Tokyo 1138549, Japan