POLYALKYLENES USED AS STATIONARY PHASES FOR PREPARATIVE REVERSED-PHASE LIQUID-CHROMATOGRAPHY

被引：8
|
作者：
KRAUSE, E [1 ]
SMETTAN, D [1 ]
LOTH, F [1 ]
HERMA, H [1 ]
机构：
[1] ACAD SCI GDR,INST POLYMER CHEM,TELTOW,GERMANY
来源：
JOURNAL OF CHROMATOGRAPHY | 1990年 / 520卷
关键词：
D O I：
10.1016/0021-9673(90)85110-H
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Polyethylene and polypropylene were employed as stationary phases for preparative liquid chromatography and compared with LiChroprep RP-18. Polyalkylene phases are chemically stable and have homogeneous hydrophobic surfaces, but they are physically less resistant than silica-based phases. The influence of organic modifiers and salt ions on the capacity factors of aromatic hydrocarbons and peptides was determined. Peptides prepared by solid-phase peptide synthesis were purified on polypropylene. The results demonstrate the usefulness of polyalkylenes in preparative reversed-phase liquid chromatography, particularly for basic peptides. © 1990.
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页码：263 / 269
页数：7
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