RAF-1 IS ESSENTIAL FOR BOTH THE LPS-INDUCED ACTIVATION OF MAP KINASES IN MACROPHAGES (MO) AND FOR THEIR TRANSLOCATION TO THE NUCLEUS

被引：0
|
作者：
GUAN, RJ
REENSTRA, W
FRENDL, G
机构：
[1] COLUMBIA MED CTR,ST LUKES HOSP,BOSTON,MA 02115
[2] BOSTON UNIV,MED CTR,DEPT DERMATOL,BOSTON,MA 02115
[3] HARVARD UNIV,BRIGHAM & WOMENS HOSP,SCH MED,BOSTON,MA 02115
来源：
FASEB JOURNAL | 1995年 / 9卷 / 04期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：A779 / A779
页数：1
相关论文
共 50 条
  • [1] GENERATION OF PHOSPHORYLCHOLINE AS AN ESSENTIAL EVENT IN THE ACTIVATION OF RAF-1 AND MAP-KINASES IN GROWTH FACTORS-INDUCED MITOGENIC STIMULATION
    JIMENEZ, B
    DELPESO, L
    MONTANER, S
    ESTEVE, P
    LACAL, JC
    JOURNAL OF CELLULAR BIOCHEMISTRY, 1995, 57 (01) : 141 - 149
  • [2] LPS-INDUCED PROTEIN TYROSINE PHOSPHORYLATION IN MACROPHAGES IS MEDIATED BY CD14 AND LEADS TO THE ACTIVATION OF MAP KINASES
    WEINSTEIN, SL
    JUNE, CH
    SANGHERA, JS
    PELECH, SL
    DEFRANCO, AL
    JOURNAL OF CELLULAR BIOCHEMISTRY, 1993, : 277 - 277
  • [3] Lyn, Jak2, and Raf-1 kinases are critical for the antiapoptotic effect of interleukin 5, whereas only Raf-1 kinase is essential for eosinophil activation and degranulation
    Pazdrak, K
    Olszewska-Pazdrak, B
    Stafford, S
    Garofalo, RP
    Alam, R
    JOURNAL OF EXPERIMENTAL MEDICINE, 1998, 188 (03): : 421 - 429
  • [4] The IL-5 signaling through Jak-2, Lyn and Raf-1 kinases is essential for eosinophil viability whereas Raf-1 is also required for priming and activation of eosinophils.
    Pazdrak, K
    Pazdrak, B
    Garofalo, R
    Alam, R
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1997, 99 (01) : 545 - 545
  • [5] STUDY OF THE LIPOPOLYSACCHARIDE-INDUCED MAP KINASE CASCADE IN MURINE MACROPHAGES USING A REGULATABLE FORM OF RAF-1
    HAMBLETON, J
    MCMAHON, M
    DEFRANCO, AL
    BLOOD, 1994, 84 (10) : A134 - A134
  • [6] PKC ζ is required for LPS-induced activation of MEK and p42/44 MAP kinase in alveolar macrophages.
    Monick, MM
    Carter, AB
    Flaherty, DM
    Peterson, MW
    Hunninghake, DM
    FASEB JOURNAL, 2000, 14 (04): : A592 - A592
  • [7] Pre-activation basal level of nuclear NF-kB in native macrophages speeds LPS-induced translocation of cytosolic NF-B into the cell nucleus
    Bagaev, A.
    Garaeva, A.
    Lebedeva, E.
    Pichugin, A.
    Ataullakhanov, R.
    Ataullakhanov, F.
    FEBS JOURNAL, 2017, 284 : 98 - 99
  • [8] Macrolides and ketolides suppress LPS-induced cytokine expression by inhibition of JNK and P38 MAP-kinases in J-774A.1 macrophages
    Lotter, K
    Höcherl, K
    Kees, F
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2006, 372 : 75 - 75
  • [9] Activation of β1 adrenoceptors promotes LPS-induced NGF secretion in macrophages via Notch signaling pathways
    Cao, Zhong-Ming
    Lei, Qian
    Xu, Hua-Li
    Wang, Sheng
    Xu, Shi-Yuan
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2019, 12 (02): : 1640 - 1648
  • [10] Inhibition of PKCβ down-regulates LPS-induced STAT1 activation and no production in macrophages
    Salonen, T
    Sareila, O
    Jalonen, U
    Kankaanranta, H
    Tuominen, RK
    Moilanen, E
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2006, 28 : S22 - S22
12345