FORMATION OF PARA-HYDROXYBENZOIC ACID FROM PARA-COUMARIC ACID BY CELL-FREE-EXTRACT OF LITHOSPERMUM-ERYTHRORHIZON CELL-CULTURES

被引：57
|
作者：
YAZAKI, K [1 ]
HEIDE, L [1 ]
TABATA, M [1 ]
机构：
[1] KYOTO UNIV,FAC PHARMACEUT SCI,DEPT PHARMACOGNOSY,KYOTO 606,JAPAN
来源：
PHYTOCHEMISTRY | 1991年 / 30卷 / 07期
关键词：
LITHOSPERMUM-ERYTHRORHIZON; BORAGINACEAE; CELL CULTURE; BIOSYNTHESIS; PARA-HYDROXYBENZOIC ACID; PARA-COUMARIC ACID; PARA-HYDROXYBENZALDEHYDE; SHIKONIN;
D O I：
10.1016/0031-9422(91)83620-Z
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The enzymatic formation of p-hydroxybenzoic acid from p-coumaric acid has been detected in cell free extracts of Lithospermum erythrorhizon cell cultures. In the absence of NAD, p-hydroxybenzaldehyde is formed instead of p-hydroxybenzoic acid. The reaction is specific to p-coumaric acid. In addition, a p-hydroxybenzaldehyde dehydrogenase activity is also found. The results suggest that the reaction mechanism is non-oxidative.
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页码：2233 / 2236
页数：4
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