STRUCTURE AND FUNCTION OF GENES IN THE MHC CLASS-II REGION

被引：32

作者：

MONACO, JJ

机构：

[1] Medical College of Virginia, Virginia Commonwealth University

来源：

CURRENT OPINION IN IMMUNOLOGY | 1993年 / 5卷 / 01期

关键词：

D O I：

10.1016/0952-7915(93)90075-4

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Genes required for antigen processing map to the MHC class II region. For the endogenous (class I) antigen processing pathway, many hypotheses concerning the structure and function of the corresponding gene products have been verified during the past year. The identity of the gene(s) involved in the exogenous (class II) pathway remains to be determined.

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页码：17 / 20

页数：4

相关论文

共 23 条

[1] ENDOGENOUSLY SYNTHESIZED PEPTIDE WITH AN ENDOPLASMIC-RETICULUM SIGNAL SEQUENCE SENSITIZES ANTIGEN PROCESSING MUTANT-CELLS TO CLASS-I-RESTRICTED CELL-MEDIATED LYSIS [J].

ANDERSON, K ;

CRESSWELL, P ;

GAMMON, M ;

HERMES, J ;

WILLIAMSON, A ;

ZWEERINK, H .

JOURNAL OF EXPERIMENTAL MEDICINE, 1991, 174 (02) :489-492

[2] PROTEASOME SUBUNITS ENCODED IN THE MHC ARE NOT GENERALLY REQUIRED FOR THE PROCESSING OF PEPTIDES BOUND BY MHC CLASS-I MOLECULES [J].

ARNOLD, D ;

DRISCOLL, J ;

ANDROLEWICZ, M ;

HUGHES, E ;

CRESSWELL, P ;

SPIES, T .

NATURE, 1992, 360 (6400) :171-174

[3] HAM-2 CORRECTS THE CLASS-I ANTIGEN-PROCESSING DEFECT IN RMA-S CELLS [J].

ATTAYA, M ;

JAMESON, S ;

MARTINEZ, CK ;

HERMEL, E ;

ALDRICH, C ;

FORMAN, J ;

LINDAHL, KF ;

BEVAN, MJ ;

MONACO, JJ .

NATURE, 1992, 355 (6361) :647-649

[4] NOMENCLATURE FOR FACTORS OF THE HLA SYSTEM, 1991 [J].

BODMER, JG ;

MARSH, SGE ;

ALBERT, ED ;

BODMER, WF ;

DUPONT, B ;

ERLICH, HA ;

MACH, B ;

MAYR, WR ;

PARHAM, P ;

SASAZUKI, T ;

SCHREUDER, GMT ;

STROMINGER, JL ;

SVEJGAARD, A ;

TERASAKI, PI .

TISSUE ANTIGENS, 1992, 39 (04) :161-173

[5]

CEMAN S, 1992, J IMMUNOL, V149, P754

[6] NEW CLASS-II-LIKE GENES IN THE MURINE MHC [J].

CHO, SG ;

ATTAYA, M ;

MONACO, JJ .

NATURE, 1991, 353 (6344) :573-576

[7] ALLELIC VARIANTS OF THE HUMAN PUTATIVE PEPTIDE TRANSPORTER INVOLVED IN ANTIGEN PROCESSING [J].

COLONNA, M ;

BRESNAHAN, M ;

BAHRAM, S ;

STROMINGER, JL ;

SPIES, T .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (09) :3932-3936

[8] THE ALPHA-CHAIN GENE OF H-2O HAS AN UNEXPECTED LOCATION IN THE MAJOR HISTOCOMPATIBILITY COMPLEX [J].

KARLSSON, L ;

PETERSON, PA .

JOURNAL OF EXPERIMENTAL MEDICINE, 1992, 176 (02) :477-483

[9] A NOVEL CLASS-II MHC MOLECULE WITH UNUSUAL TISSUE DISTRIBUTION [J].

KARLSSON, L ;

SURH, CD ;

SPRENT, J ;

PETERSON, PA .

NATURE, 1991, 351 (6326) :485-488

[10] ASSEMBLY AND FUNCTION OF THE 2 ABC TRANSPORTER PROTEINS ENCODED IN THE HUMAN MAJOR HISTOCOMPATIBILITY COMPLEX [J].

KELLY, A ;

POWIS, SH ;

KERR, LA ;

MOCKRIDGE, I ;

ELLIOTT, T ;

BASTIN, J ;

UCHANSKAZIEGLER, B ;

ZIEGLER, A ;

TROWSDALE, J ;

TOWNSEND, A .

NATURE, 1992, 355 (6361) :641-644