NA+-ACTIVATED K+ CHANNELS ARE WIDELY DISTRIBUTED IN RAT CNS AND IN XENOPUS OOCYTES

被引：50
|
作者：
EGAN, TM
DAGAN, D
KUPPER, J
LEVITAN, IB
机构：
[1] BRANDEIS UNIV,GRAD DEPT BIOCHEM,WALTHAM,MA 02254
[2] BRANDEIS UNIV,CTR COMPLEX SYST,WALTHAM,MA 02254
[3] TECHNION ISRAEL INST TECHNOL,FAC MED,RAPPAPORT FAMILY INST,DEPT PHYSIOL & BIOPHYS,IL-30197 HAIFA,ISRAEL
[4] ST LOUIS UNIV,SCH MED,DEPT PHARMACOL & PHYSIOL SCI,ST LOUIS,MO 63104
来源：
BRAIN RESEARCH | 1992年 / 584卷 / 1-2期
关键词：
OLFACTORY BULB; POTASSIUM CHANNEL; SODIUM-ACTIVATED; XENOPUS OOCYTE;
D O I：
10.1016/0006-8993(92)90913-T
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
We recorded the activity of K+ channels activated by sodium (K(Na) channels) in two widely used preparations, prima cell cultures prepared from neocortex, cerebellum, midbrain, brainstem and spinal cord, and Xenopus oocytes. K(Na) channels from all regions shared an absolute dependence on [Na+], had conductances of 140-170 pS in symmetrical 150 mM K+ and exhibited characteristic substates. The role of this channel must now be considered in terms of its widespread distribution.
引用
收藏
页码：319 / 321
页数：3
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