DEGRADATION OF DNA-RNA HYBRIDS BY BLEOMYCIN - EVIDENCE FOR DNA STRAND SPECIFICITY AND FOR POSSIBLE STRUCTURAL MODULATION OF CHEMICAL MECHANISM

被引：32
|
作者：
KRISHNAMOORTHY, CR
VANDERWALL, DE
KOZARICH, JW
STUBBE, J
机构：
[1] UNIV MARYLAND,DEPT CHEM & BIOCHEM,COLLEGE PK,MD 20742
[2] UNIV WISCONSIN,DEPT BIOCHEM,MADISON,WI 53706
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1988年 / 110卷 / 06期
关键词：
D O I：
10.1021/ja00214a079
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
引用
收藏
页码：2008 / 2009
页数：2
相关论文
共 18 条
  • [1] Effects of hypoxanthine substitution on bleomycin-mediated DNA strand degradation in DNA-RNA hybrids
    Bansal, M
    Stubbe, J
    Kozarich, JW
    NUCLEIC ACIDS RESEARCH, 1997, 25 (09) : 1846 - 1853
  • [2] CHEMISTRY OF BLEOMYCIN ATTACK ON DNA-RNA HYBRIDS AND DNAS
    KRISHNAMOORTHY, CR
    VANDERWALL, D
    MCGALL, G
    RABOW, L
    ABSALON, M
    STUBBE, J
    KOZARICH, JW
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1988, 196 : 15 - MEDI
  • [3] CONFORMATIONAL AND CHEMICAL-ANALYSIS OF DNA-RNA HYBRID DEGRADATION BY BLEOMYCIN
    BANSAL, M
    LEE, JS
    VANDERWALL, DE
    ZHANG, G
    ZHANG, X
    STUBBE, J
    KOZARICH, JW
    FASEB JOURNAL, 1993, 7 (07): : A1089 - A1089
  • [4] SEQUENCE SPECIFIC DEGRADATION OF A DNA-RNA HYBRID BY BLEOMYCIN
    LEE, JS
    KOZARICH, JW
    STUBBE, J
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1990, 199 : 103 - BIOL
  • [5] BLEOMYCIN MEDIATED DEGRADATION OF DNA-RNA HYBRIDS DOES NOT INVOLVE C-1' CHEMISTRY
    ABSALON, MJ
    KRISHNAMOORTHY, CR
    MCGALL, G
    KOZARICH, JW
    STUBBE, J
    NUCLEIC ACIDS RESEARCH, 1992, 20 (16) : 4179 - 4185
  • [6] SEQUENCE-SPECIFIC DEGRADATION OF A DNA-RNA HYBRID BY BLEOMYCIN
    LEE, JS
    KOZARICH, JW
    STUBBE, J
    BIOCHEMISTRY, 1990, 29 (08) : 2198 - 2198
  • [7] IRON(II) BLEOMYCIN-MEDIATED DEGRADATION OF A DNA-RNA HETERODUPLEX
    MORGAN, MA
    HECHT, SM
    BIOCHEMISTRY, 1994, 33 (34) : 10286 - 10293
  • [8] Mechanistic analyses of site-specific degradation in DNA-RNA hybrids by prototypic DNA cleavers
    Bansal, M
    Lee, JS
    Stubbe, J
    Kozarich, JW
    NUCLEIC ACIDS RESEARCH, 1997, 25 (09) : 1836 - 1845
  • [9] AUTOMATED PREPARATION OF DNA-RNA HYBRIDS AND THEIR JOINING WITH RNA LIGASE - AN APPROACH TO SINGLE-STRAND GENE SYNTHESIS
    ZEH, D
    SELIGER, H
    NUCLEOSIDES & NUCLEOTIDES, 1987, 6 (1-2): : 485 - 488
  • [10] Sequence-specific cleavage of the RNA strand in DNA-RNA hybrids by the fusion of ribonuclease H with a zinc finger
    Sulej, Agata A.
    Tuszynska, Irina
    Skowronek, Krzysztof J.
    Nowotny, Marcin
    Bujnicki, Janusz M.
    NUCLEIC ACIDS RESEARCH, 2012, 40 (22) : 11563 - 11570
12