CONSTANT HELICAL PITCH OF THE GRAMICIDIN CHANNEL IN PHOSPHOLIPID-BILAYERS

被引：40

作者：

KATSARAS, J

PROSSER, RS

STINSON, RH

DAVIS, JH

机构：

[1] Department of Physics, University of Guelph, Ontario

来源：

BIOPHYSICAL JOURNAL | 1992年 / 61卷 / 03期

基金：

加拿大自然科学与工程研究理事会;

关键词：

D O I：

10.1016/S0006-3495(92)81888-X

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

X-ray diffraction has been applied in measuring the helical pitch of the gramicidin channel in oriented bilayers of dilauroylphosphatidylcholine (DLPC) and dimyristoylphosphatidylcholine (DMPC) at a polypeptide concentration of 9.1 mol %. The diffraction data show the helical pitch of gramicidin to be 4.7 +/- 0.2 angstrom in both gel and liquid-crystalline phase bilayers, with and without monovalent cations. In addition, the width of the reflection due to the pitch of the helical gramicidin channel is consistent with a five turn helix.

引用

页码：827 / 830

页数：4

共 21 条

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ANDERSEN OS, 1984, ANNU REV PHYSIOL, V46, P531

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