PHARMACOKINETIC AND PHARMACODYNAMIC INTERACTION BETWEEN LUMIRACOXIB AND FLUVASTATIN

被引：0
|
作者：
Anbu, Jayaraman [1 ]
Anjana, Ashwini [1 ]
Roosewelt, C. [1 ]
Rao, G. Srinivasa [1 ]
Sathish, R. [2 ]
机构：
[1] VISTAS Vels Univ, Sch Pharmaceut Sci, Dept Pharmacol & Toxicol, Chennai 600117, Tamil Nadu, India
[2] NIS, Dept Toxicol, Chennai 600044, Tamil Nadu, India
来源：
INTERNATIONAL JOURNAL OF LIFE SCIENCE AND PHARMA RESEARCH | 2012年 / 2卷 / 02期
关键词：
Lumiracoxib; Fluvastatin; COX-2; inhibitors; Rheumatoid arthritis; Hypolipidemic;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The present study was carried out to investigate the pharmacokinetics and pharmacodynamic interaction between Lumiracoxib (20mg/kg p.o.) and Fluvastatin (5mg/kg p.o.) alone and their combination in rats by open labeled parallel study design. The animals were maintained on a standard laboratory conditions and were divided into 3 and 6 groups for Pharmacokinetic and Pharmacodynamic studies respectively.
引用
收藏
页码：P42 / P50
页数：9
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