DIHYDROPYRIDINES - A NEW CLASS OF ANGIOTENSIN-II ANTAGONISTS

被引：6
|
作者：
WESTER, RT
MULARSKI, CJ
MAGNUSAYRITEY, GT
JARDINE, PD
LAFLAMME, JA
BERKE, H
BUSSOLOTTI, DL
RAUCH, AL
HOOVER, KW
KENNEDY, CA
BURKARD, MR
MANGIAPANE, ML
ALDINGER, CE
COOPER, K
CARPINO, PA
机构：
[1] PFIZER INC,CENT RES,DEPT MED CHEM,GROTON,CT 06340
[2] PFIZER INC,CENT RES,DEPT METAB DIS,GROTON,CT 06340
[3] PFIZER LTD,CENT RES,DEPT DISCOVERY CHEM,SANDWICH CT13 9NJ,KENT,ENGLAND
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1994年 / 4卷 / 01期
关键词：
D O I：
10.1016/S0960-894X(01)81135-5
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The syntheses and biological activities of dihydropyridine angiotensin II (AII) antagonists are described. Compounds such as 12 are examples of a new, structurally distinct class of AT(1)-selective agents.
引用
收藏
页码：133 / 138
页数：6
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