TOPICAL IMMUNOGLOBULINS FOR EPITHELIAL HERPES-SIMPLEX KERATITIS

被引：0

作者：

KLAGER, AJ

BUCHI, ER

OSUSKY, R

BUREKKOZLOWSKA, A

MORELL, A

机构：

[1] SWISS RED CROSS,BLOOD TRANSFUS SERV,CENT LAB,WANKDORFSTR 10,CH-3000 BERN 22,SWITZERLAND

[2] UNIV BASEL,HOSP EYE,CH-4051 BASEL,SWITZERLAND

来源：

OPHTHALMOLOGICA | 1993年 / 207卷 / 02期

关键词：

HERPES SIMPLEX; EPITHELIAL KERATITIS; TOPICAL IMMUNOGLOBULINS;

D O I：

暂无

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

A new immunoglobulin preparation for topical administration in the eye has been developed. The tolerance to this preparation was tested in a phase I/II study, in combination with the antiviral drug trifluorothymidine, in 5 patients with untreated episodes of herpes simplex epithelial keratitis. The clinical course of these patients was within usual limits, with a mean healing time of 6.6 days (range 2-15 days). No undesirable effects were observed. Our findings suggest that this new treatment modality is safe and offers a new perspective, but additional studies are required to determine its efficacy.

引用

页码：78 / 81

页数：4

共 11 条

[1]

BONAMOUR M, 1959, B SOC OPHTHALMOL FR, V56, P438

[2]

CUCCAGNA F, 1956, G ITAL OFTALMOL, V9, P671

[3] BLUNT SPATULA DEBRIDEMENT AND TRIFLUOROTHYMIDINE IN EPITHELIAL HERPETIC-KERATITIS [J].