RE-EXAMINATION OF INFLUENCE OF MUSCLE LENGTH ON MYOCARDIAL PERFORMANCE

被引：233

作者：

JEWELL, BR ^{[1
]}

机构：

[1] UCL, DEPT PHYSIOL, LONDON WC1E 6BT, ENGLAND

来源：

CIRCULATION RESEARCH | 1977年 / 40卷 / 03期

关键词：

D O I：

10.1161/01.RES.40.3.221

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Length-dependence of activation accounted almost entirely for the dependence of tension production on muscle length over the ascending limb of the length-tension relation in isolated [frog, rat, cat and rabbit] papillary muscles. If the inotropic state of the muscle was equated with the degree of activation of the contractile system, then muscle length influenced inotropic state and a change of muscle length must be regarded as an inotropic intervention. If these results were applicable to the intact heart, then diastolic volume and inotropic state could not be regarded as independent regulators of cardiac output.

引用

页码：221 / 230

页数：10

共 54 条

[1]

ALLEN DG, 1976, J PHYSIOL-LONDON, V254, P1

[2] CONTRIBUTION OF ACTIVATION PROCESSES TO LENGTH-TENSION RELATION OF CARDIAC-MUSCLE [J].