THE PHARMACOKINETICS OF (+)-PRIMAQUINE AND (-)-PRIMAQUINE IN THE ISOLATED PERFUSED-RAT-LIVER PREPARATION

被引：7
作者：
WARD, SA
MIHALY, GW
NICHOLL, DD
BRECKENRIDGE, AM
EDWARDS, G
机构：
[1] UNIV LIVERPOOL, DEPT PHARMACOL & THERAPEUT, LIVERPOOL L69 3BX, ENGLAND
[2] UNIV LIVERPOOL, LIVERPOOL SCH TROP MED, DEPT TROP MED, LIVERPOOL L3 5QA, ENGLAND
来源：
BIOCHEMICAL PHARMACOLOGY | 1987年 / 36卷 / 13期
关键词：
D O I：
10.1016/0006-2952(87)90160-2
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：2238 / 2239
页数：2
相关论文
共 11 条
[1]  
BRECKENRIDGE A, 1974, CLIN PHARMACOL THER, V15, P424
[2]   RESOLUTION OF ANTI-MALARIAL AGENTS VIA COMPLEX-FORMATION WITH ALPHA-(2,4,5,7-TETRANITRO-9-FLUORENYLIDENEAMINOOXY)PROPIONIC ACID [J].
CARROLL, FI ;
BERRANG, B ;
LINN, CP .
JOURNAL OF MEDICINAL CHEMISTRY, 1978, 21 (04) :326-330
[3]   THE EFFECTS OF PRIMAQUINE STEREOISOMERS AND METABOLITES ON DRUG-METABOLISM IN THE ISOLATED PERFUSED RAT-LIVER AND INVITRO RAT LIVER-MICROSOMES [J].
MIHALY, GW ;
WARD, SA ;
NICHOLL, DD ;
EDWARDS, G ;
BRECKENRIDGE, AM .
BIOCHEMICAL PHARMACOLOGY, 1985, 34 (03) :331-336
[4]   H2-RECEPTOR ANTAGONISTS AND HEPATIC DRUG DISPOSITION [J].
MIHALY, GW ;
SMALLWOOD, RA ;
ANDERSON, JD ;
JONES, DB ;
WEBSTER, LK ;
VAJDA, FJ .
HEPATOLOGY, 1982, 2 (06) :828-831
[5]   PHARMACOKINETICS OF PRIMAQUINE IN MAN .1. STUDIES OF THE ABSOLUTE BIOAVAILABILITY AND EFFECTS OF DOSE SIZE [J].
MIHALY, GW ;
WARD, SA ;
EDWARDS, G ;
NICHOLL, DD ;
LEORME, M ;
BRECKENRIDGE, AM .
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1985, 19 (06) :745-750
[6]  
OREILLY RA, 1974, CLIN PHARMACOL THER, V16, P348
[7]   COMPARISON OF CURATIVE ANTIMALARIAL ACTIVITIES AND TOXICITIES OF PRIMAQUINE AND ITS D AND L ISOMERS [J].
SCHMIDT, LH ;
ALEXANDER, S ;
ALLEN, L ;
RASCO, J .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1977, 12 (01) :51-60
[8]   STEREOSELECTIVE DISPOSITION AND GLUCURONIDATION OF PROPRANOLOL IN HUMANS [J].
SILBER, B ;
HOLFORD, NHG ;
RIEGELMAN, S .
JOURNAL OF PHARMACEUTICAL SCIENCES, 1982, 71 (06) :699-704
[9]  
WARD SA, 1985, DRUG METAB DISPOS, V13, P425
[10]   DETERMINATION OF PRIMAQUINE IN BIOLOGICAL-FLUIDS BY REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].
WARD, SA ;
EDWARDS, G ;
ORME, ML ;
BRECKENRIDGE, AM .
JOURNAL OF CHROMATOGRAPHY, 1984, 305 (01) :239-243
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