SYNERGY OF CEFOTAXIME AND FOSFOMYCIN AGAINST PENICILLIN-RESISTANT PNEUMOCOCCI

被引:28
作者
BARAKETT, V
LESAGE, D
DELISLE, F
BURGHOFFER, B
RICHARD, G
VERGEZ, P
PETIT, JC
机构
[1] Laboratoire Central de Microbiologie, 75012 Paris, CHU Saint-Antoine
关键词
D O I
10.1093/jac/31.1.105
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The killing kinetics of cefotaxime and fosfomycin, alone and in combination, against seven clinical isolates of penicillin-resistant pneumococci were studied. The antibiotics were tested at 1 ×, 2 × and 4 × the MIC for each individual isolate. The results showed a synergic interaction of the two antibiotics for three of the seven strains. This strategy may be useful clinically. © 1993 The British Society for Antimicrobial Chemotherapy.
引用
收藏
页码:105 / 109
页数:5
相关论文
共 9 条
[1]   INTERNATIONAL COLLABORATIVE STUDY ON STANDARDIZATION OF BACTERIAL SENSITIVITY TO FOSFOMYCIN [J].
ANDREWS, JM ;
BAQUERO, F ;
BELTRAN, JM ;
CANTON, E ;
CROKAERT, F ;
GOBERNADO, M ;
GOMEZLUS, R ;
LOZA, E ;
NAVARRO, M ;
OLAY, T ;
RODRIGUEZ, A ;
VICENTE, MV ;
WISE, R ;
YOURASSOWSKY, E .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1983, 12 (04) :357-361
[2]   A REVIEW OF ANTIBIOTIC-RESISTANCE PATTERNS OF STREPTOCOCCUS-PNEUMONIAE IN EUROPE [J].
BAQUERO, F ;
MARTINEZBELTRAN, J ;
LOZA, E .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1991, 28 :31-38
[3]   PENICILLIN RESISTANT PNEUMOCOCCI IN FRANCE AND BETA-LACTAM AGENTS - UPDATE OF THE CENTER-NATIONAL-DE-REFERENCE [J].
GESLIN, P ;
FREMAUX, A ;
SISSIA, G .
MEDECINE ET MALADIES INFECTIEUSES, 1991, 21 (4BIS) :3-11
[4]   EMERGENCE OF MULTIPLY RESISTANT PNEUMOCOCCI [J].
JACOBS, MR ;
KOORNHOF, HJ ;
ROBINSBROWNE, RM ;
STEVENSON, CM ;
VERMAAK, ZA ;
FREIMAN, I ;
MILLER, GB ;
WITCOMB, MA ;
ISAACSON, M ;
WARD, JI ;
AUSTRIAN, R .
NEW ENGLAND JOURNAL OF MEDICINE, 1978, 299 (14) :735-740
[5]  
JAWETZ E, 1968, ANTIMICROB AGENTS CH, P203
[6]   PHARMACOKINETICS AND BACTERIOLOGIC EFFICACY OF MOXALACTAM, CEFOTAXIME, CEFOPERAZONE, AND ROCEPHIN IN EXPERIMENTAL BACTERIAL-MENINGITIS [J].
SCHAAD, UB ;
MCCRACKEN, GH ;
LOOCK, CA ;
THOMAS, ML .
JOURNAL OF INFECTIOUS DISEASES, 1981, 143 (02) :156-163
[7]  
SOUSSY CJ, 1990, BACTERICIDE, P173
[8]   CHARACTERISTICS AND ANTIBIOTIC-THERAPY OF ADULT MENINGITIS DUE TO PENICILLIN-RESISTANT PNEUMOCOCCI [J].
VILADRICH, PF ;
GUDIOL, F ;
LINARES, J ;
RUFI, G ;
ARIZA, J ;
PALLARES, R .
AMERICAN JOURNAL OF MEDICINE, 1988, 84 (05) :839-846
[9]   EFFECT OF ANTIBIOTIC CARRY-OVER ON BACTERIAL COUNTING BY SPIRAL PLATING [J].
YOURASSOWSKY, E ;
VANDERLINDEN, MP ;
CROKAERT, F ;
GLUPCZYNSKI, Y .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1988, 21 (01) :138-140