THE EFFECTS OF CENTRAL NOREPINEPHRINE INFUSIONS ON DRINKING BEHAVIOR INDUCED BY ANGIOTENSIN AFTER 6-HYDROXYDOPAMINE INJECTIONS INTO THE ANTEROVENTRAL REGION OF THE 3RD VENTRICLE (AV3V)

被引：35

作者：

CUNNINGHAM, JT

JOHNSON, AK

机构：

[1] UNIV IOWA, DEPT PHARMACOL, IOWA CITY, IA 52242 USA

[2] UNIV IOWA, CTR CARDIOVASC, IOWA CITY, IA 52242 USA

来源：

BRAIN RESEARCH | 1991年 / 558卷 / 01期

关键词：

THIRST; ORGANUM VASCULOSUM OF THE LAMINA TERMINALIS; MEDIAN PREOPTIC NUCLEUS; CATECHOLAMINE; DIPSOGEN;

D O I：

10.1016/0006-8993(91)90724-A

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Adult male Sprague-Dawley rats were injected with either 6-hydroxydopamine (6-OHDA) or vehicle in the median preoptic nucleus and the organum vasculosum of the lamina terminalis. The subjects were tested for drinking responses to intraventricular angiotensin II (ANG II) or saline during either saline or norepinephrine intraventricular infusions. Rats injected with 6-OHDA into the ventral lamina terminalis initially failed to show drinking responses to ANG II injections. However, norepinephrine infusion in combination with ANG II injection restored the drinking response to ANG II in rats with catecholamine depletions of the lamina terminalis region.

引用

页码：112 / 116

页数：5

共 17 条

[1]

ANTELMAN SM, 1988, SENSITIZATION NERVOU, P227

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