ENZYMATIC RESOLUTION OF RACEMIC GLYCALS - AN APPLICATION OF THE WONG ACYLATION METHOD

被引：18

作者：

BERKOWITZ, DB ^{[1
]}

DANISHEFSKY, SJ ^{[1
]}

机构：

[1] YALE UNIV,DEPT CHEM,NEW HAVEN,CT 06511

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 40期

关键词：

D O I：

10.1016/0040-4039(91)80067-G

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Kinetic resolution of racemic, fully synthetic, artificial glycals bearing a free hydroxyl group at C3 was accomplished through the more rapid acylation of the ''D''-antipode with vinyl acetate as acyl donor and Lipase PS-30 from Pseudomonas cepacia as catalyst.

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页码：5497 / 5500

页数：4

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