A NEW SYNTHON FOR OPTICALLY-ACTIVE DIENE HYDROPEROXIDES

被引：24

作者：

DUSSAULT, P

LEE, IQ

KREIFELS, S

机构：

[1] Department of Chemistry, University of Nebraska—Lincoln, Lincoln

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1991年 / 56卷 / 13期

关键词：

D O I：

10.1021/jo00013a001

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The olefination of an enzymatically derived gamma-peroxy-alpha,beta-unsaturated aldehyde (1) allows the synthesis of optically active diene hydroperoxides in high enantiomeric excess. The application of this method to the synthesis of 13(S)-hydroperoxy-9(Z),11(E)-octadecadienoic acid methyl ester is presented.

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页码：4087 / 4089

页数：3

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