A NEW ACCESS TO 2-(CHLOROMETHYL)ACRYLONITRYLE

被引：7
作者：
KRAWCZYK, H
机构：
[1] Institute of Organic Chemistry, Technical University (Politechnika), 90-924 Łódź
来源：
SYNTHETIC COMMUNICATIONS | 1995年 / 25卷 / 21期
关键词：
D O I：
10.1080/00397919508013856
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient method for the preparation of 2-(chloromethyl)acrylonitrile (7) is reported. The Mannich reaction of cyanoacetic acid with paraformaldehyde and morpholine afforded the allylic amine 6a which was converted into the chloride 7 on treatment with isobutyl chloroformate at room temperature.
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页码：3357 / 3362
页数：6
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