Clinical features and treatment of maturity onset diabetes of the young (MODY)

被引：91

作者：

Gardner, Daphne S. L. ^{[1
]}

Tai, E. Shyong ^{[2
]}

机构：

[1] Singapore Gen Hosp, Dept Endocrinol, Block 6,Level 6,Outram Rd, Singapore 169608, Singapore

[2] Natl Univ Singapore Hosp, Dept Endocrinol, Singapore, Singapore

来源：

DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY | 2012年 / 5卷

关键词：

type; 1; diabetes; 2; HNF1A; HNF4A; HNF1B; GCK;

D O I：

10.2147/DMSO.S23353

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Maturity onset diabetes of the young (MODY) is a heterogeneous group of disorders that result in beta-cell dysfunction. It is rare, accounting for just 1%-2% of all diabetes. It is often misdiagnosed as type 1 or type 2 diabetes, as it is often difficult to distinguish MODY from these two forms. However, diagnosis allows appropriate individualized care, depending on the genetic etiology, and allows prognostication in family members. In this review, we discuss features of the common causes of MODY, as well as the treatment and diagnosis of MODY.

引用

页码：101 / 108

页数：8

共 84 条

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