SYNTHESIS AND PRELIMINARY CHEMILUMINESCENCE AND BIOLUMINESCENCE STUDIES OF A NOVEL PHOTOLABILE COELENTERAZINE ANALOG WITH A TRIFLUOROMETHYL DIAZIRINE GROUP

被引：6
作者：
CHEN, FQ
HIRANO, T
HASHIZUME, Y
OHMIYA, Y
OHASHI, M
机构：
[1] UNIV ELECTROCOMMUN,DEPT APPL PHYS & CHEM,CHOFU,TOKYO 182,JAPAN
[2] INST PHYS & CHEM RES,SOLAR ENERGY RES GRP,JRDC,PRESTO,WAKO,SAITAMA 35101,JAPAN
来源：
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1994年 / 20期
关键词：
D O I：
10.1039/c39940002405
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel photolabile analogue of coelenterazine with a trifluoromethyl diazirine group is successfully synthesized for photoaffinity labelling of the active site of aequorin; preliminary studies on its chemi- and bio-luminescence demonstrate that the photolabile analogue shows the same luminescence properties and kinetics as those of natural coelenterazine and thus, it is deduced that both compounds occupy the same active site; of aequorin.
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页码：2405 / 2406
页数：2
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