PLANT-CELL AND TISSUE-CULTURE - ALTERNATIVES FOR METABOLITE PRODUCTION

被引:117
|
作者
DICOSMO, F
MISAWA, M
机构
[1] UNIV TORONTO, INST BIOMED ENGN, TORONTO, ON M5S 3B2, CANADA
[2] BIO INT INC, TORONTO, ON M5S 1S4, CANADA
关键词
PLANT CELL CULTURE TECHNOLOGY; SECONDARY METABOLITES; PHARMACEUTICALS; MEDICINAL COMPOUNDS;
D O I
10.1016/0734-9750(95)02005-N
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Plant cell culture systems represent a potential renewable source of valuable medicinals, flavours,essences and colourants that cannot be produced by microbial cells or chemical syntheses. However, only a few cultures produce these compounds in commercially useful amounts, The low productivities are associated with our poor understanding of the biochemistry of these systems, Recent advances in molecular biology, enzymology, physiology and fermentation technology of plant cell cultures suggest that these systems will become a viable source of important natural products, This review examines the sate of the art of production of medicinal plant secondary metabolites by plant cell cultures.
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页码:425 / 453
页数:29
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