HYPOZINCEMIA DURING FEVER MAY TRIGGER FEBRILE CONVULSION

被引：17
作者：
IZUMI, Y
ISHII, K
AKIBA, K
HAYASHI, T
机构：
[1] Yamagata University School of Medicine, Department of Pediatrics, Yamagata-City, Yamagata
来源：
MEDICAL HYPOTHESES | 1990年 / 32卷 / 01期
关键词：
D O I：
10.1016/0306-9877(90)90073-N
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Febrile convulsions are generally thought to be induced by metabolic changes during the rise-phase of body temperature. The mechanism by which convulsions are induced, however, is not fully elucidated. In this article, we propose a new hypothesis about the induction mechanism of febrile convulsions that takes into account the hypozincemia during fever. This hypozincemia activates the NMDA receptor, one of the glutamate family of receptors, which may play an important role in the induction of epileptic discharge. © 1990.
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页码：77 / 80
页数：4
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