THE SEROTONIN-S2 RECEPTOR - A RECEPTOR-TRANSDUCER COUPLING MODEL TO EXPLAIN INSURMOUNTABLE ANTAGONIST EFFECTS

被引：49

作者：

DECOURCELLES, DC

LEYSEN, JE

ROEVENS, P

VANBELLE, H

机构：

来源：

DRUG DEVELOPMENT RESEARCH | 1986年 / 8卷 / 1-4期

关键词：

D O I：

10.1002/ddr.430080120

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：173 / 178

页数：6

共 8 条

[1] STIMULATION BY SEROTONIN OF 40-KDA AND 20-KDA PROTEIN-PHOSPHORYLATION IN HUMAN-PLATELETS [J].

DECOURCELLES, DD ;

ROEVENS, P ;

VANBELLE, H .

FEBS LETTERS, 1984, 171 (02) :289-292

[2]

DECOURCELLES DD, 1985, J BIOL CHEM, V260, P7603

[3] DRUG-RECEPTOR DISSOCIATION TIME, NEW TOOL FOR DRUG RESEARCH - RECEPTOR-BINDING AFFINITY AND DRUG-RECEPTOR DISSOCIATION PROFILES OF SEROTONIN-S2, DOPAMINE-D2, HISTAMINE-H-1 ANTAGONISTS, AND OPIATES [J].

LEYSEN, JE ;

GOMMEREN, W .

DRUG DEVELOPMENT RESEARCH, 1986, 8 (1-4) :119-131

[4] DEMONSTRATION OF S2-RECEPTOR BINDING-SITES ON CAT-BLOOD PLATELETS USING [H-3]-LABELED KETANSERIN [J].

LEYSEN, JE ;

GOMMEREN, W ;

DECLERCK, F .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1983, 88 (01) :125-130

[5]

LEYSEN JE, 1982, MOL PHARMACOL, V21, P301

[6] SEROTONIN-S2 RECEPTOR-BINDING SITES AND FUNCTIONAL CORRELATES [J].

LEYSEN, JE ;

DECOURCELLES, DD ;

DECLERCK, F ;

NIEMEGEERS, CJE ;

VANNUETEN, JM .

NEUROPHARMACOLOGY, 1984, 23 :1493-1501

[7]

VANNUETEN JM, 1981, J PHARMACOL EXP THER, V218, P217

[8]

VANNUETEN JM, 1984, J CARDIOVASC PHARM, V6, P564

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