BETA-ADRENERGIC AGONIST-MEDIATED DESENSITIZATION IN SENESCENT RATS

被引：52
作者：
SCARPACE, PJ
ABRASS, IB
机构：
[1] UNIV CALIF LOS ANGELES,SCH MED,DEPT MED,LOS ANGELES,CA 90024
[2] UNIV WASHINGTON,SCH MED,DEPT MED,SEATTLE,WA 98105
来源：
MECHANISMS OF AGEING AND DEVELOPMENT | 1986年 / 35卷 / 03期
关键词：
D O I：
10.1016/0047-6374(86)90128-4
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
引用
收藏
页码：255 / 264
页数：10
相关论文
共 19 条
[1]   ISOPROTERENOL RESPONSIVENESS AND MYOCARDIAL BETA-ADRENERGIC RECEPTORS IN YOUNG AND OLD RATS [J].
ABRASS, IB ;
DAVIS, JL ;
SCARPACE, PJ .
JOURNALS OF GERONTOLOGY, 1982, 37 (02) :156-160
[2]   CATALYTIC UNIT OF ADENYLATE-CYCLASE - REDUCED ACTIVITY IN AGED HUMAN-LYMPHOCYTES [J].
ABRASS, IB ;
SCARPACE, PJ .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1982, 55 (05) :1026-1028
[3]  
DELEAN A, 1980, J BIOL CHEM, V255, P7108
[4]  
DELEAN A, 1982, MOL PHARMACOL, V255, P5
[5]   ALTERATIONS IN LEUKOCYTE BETA-RECEPTOR AFFINITY WITH AGING - A POTENTIAL EXPLANATION FOR ALTERED BETA-ADRENERGIC SENSITIVITY IN THE ELDERLY [J].
FELDMAN, RD ;
LIMBIRD, LE ;
NADEAU, J ;
ROBERTSON, D ;
WOOD, AJJ .
NEW ENGLAND JOURNAL OF MEDICINE, 1984, 310 (13) :815-819
[6]   BETA-ADRENERGIC RECEPTORS IN AGED RAT-BRAIN - REDUCED NUMBER AND CAPACITY OF PINEAL-GLAND TO DEVELOP SUPER-SENSITIVITY [J].
GREENBERG, LH ;
WEISS, B .
SCIENCE, 1978, 201 (4350) :61-63
[7]  
GUARENIERI T, 1980, AM J PHYSL, V230, pH501
[8]   LIGAND - A VERSATILE COMPUTERIZED APPROACH FOR CHARACTERIZATION OF LIGAND-BINDING SYSTEMS [J].
MUNSON, PJ ;
RODBARD, D .
ANALYTICAL BIOCHEMISTRY, 1980, 107 (01) :220-239
[9]   ALTERATIONS IN THE PROPERTIES OF BETA-ADRENERGIC RECEPTORS OF MYOCARDIAL MEMBRANES IN AGING - IMPAIRMENTS IN AGONIST RECEPTOR INTERACTIONS AND GUANINE-NUCLEOTIDE REGULATION ACCOMPANY DIMINISHED CATECHOLAMINE-RESPONSIVENESS OF ADENYLATE-CYCLASE [J].
NARAYANAN, N ;
DERBY, JA .
MECHANISMS OF AGEING AND DEVELOPMENT, 1982, 19 (02) :127-139
[10]   AGE-ASSOCIATED DECREASE OF ADENYLATE-CYCLASE ACTIVITY IN RAT MYOCARDIUM [J].
OCONNOR, SW ;
SCARPACE, PJ ;
ABRASS, IB .
MECHANISMS OF AGEING AND DEVELOPMENT, 1981, 16 (01) :91-95
12