SECOIRIDOID AND FLAVONOID GLYCOSIDES FROM GONOCARYUM-CALLERYANUM

The leaves of Gonocaryum calleryanum afforded four new secoiridoid glycosides acylated with 2,3-dihydroxy-2-methylbutanoic acid, three of which have a novel 10-membered dilactone-ring. From this plant, we also isolated a new flavonoid glycoside, apigenin 7-O-beta-apiofuranosyl(1 --> 6)-beta-D-glucopyranoside, along with six known flavonoids and flavonoid glycosides, apigenin, apigenin-5,7-dimethyl ether, apigenin trimethyl ether, apigenin 7-O-glucoside, apigenin 7-O-neohesperidoside, and vitexin. The structure of the new glycosides was elucidated by chemical and spectral means.