SYNTHESIS OF MONOPROTECTED 2-ALKYLIDENE-1,3-PROPANEDIOLS BY AN UNUSUAL SN2' MITSUNOBU REACTION

被引：36
作者：
CHARETTE, AB
COTE, B
机构：
[1] Département de chimie, Université de Montréal, Montréal
来源：
TETRAHEDRON LETTERS | 1993年 / 34卷 / 43期
关键词：
D O I：
10.1016/S0040-4039(00)91807-0
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple and efficient route to monoprotected E- and Z-2-alkylidene-1,3-propanediols was developed. The key step involves an unusual regio- and stereoselective SN2' Mitsunobu reaction of substituted 3-hydroxy-2-methylenealkenoate.
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页码：6833 / 6836
页数：4
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