TOTAL SYNTHESIS OF (+/-)-SESBANIMIDE-A AND (+/-)-SESBANIMIDE-B

被引：32

作者：

GRIECO, PA

HENRY, KJ

NUNES, JJ

MATT, JE

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1992年 / 04期

关键词：

D O I：

10.1039/c39920000368

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The total synthesis of sesbanimide A (1) and B (2) is reported which features (a) the reaction of cyclopentadiene with glyoxylic acid leading to the useful bicyclic lactone building block 3 and (b) the use of 2.5 mol dm-3 lithium perchlorate in diethyl ether to promote the conjugate addition of 1-methoxy-1-(tert-butyldimethylsiloxy)ethene to unsaturated lactone 11.

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页码：368 / 370

页数：3

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