THE EFFICIENT SYNTHESIS AND SIMPLE RESOLUTION OF A PROLINEBORONATE ESTER SUITABLE FOR ENZYME-INHIBITION STUDIES

被引：43
作者：
KELLY, TA
FUCHS, VU
PERRY, CW
SNOW, RJ
机构：
来源：
TETRAHEDRON | 1993年 / 49卷 / 05期
关键词：
D O I：
10.1016/S0040-4020(01)86281-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A method for the preparation and resolution of the pinanediol ester of prolineboronic acid is described. The method takes advantage of the ease of both the lithiation and the reduction of boc-pyrrole to generate the desired compound rapidly and in high yield.
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页码：1009 / 1016
页数：8
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