HUMAN-LYMPHOCYTES AGED INVIVO HAVE REDUCED LEVELS OF METHYLATION IN TRANSCRIPTIONALLY ACTIVE AND INACTIVE DNA

被引：65
作者：
DRINKWATER, RD
BLAKE, TJ
MORLEY, AA
TURNER, DR
机构：
来源：
MUTATION RESEARCH | 1989年 / 219卷 / 01期
关键词：
D O I：
10.1016/0921-8734(89)90038-6
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
引用
收藏
页码：29 / 37
页数：9
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共 43 条
[1]   DISTRIBUTION OF 5-METHYLDEOXYCYTIDINE IN PRODUCTS OF STAPHYLOCOCCAL NUCLEASE DIGESTION OF NUCLEI AND PURIFIED DNA [J].
BARR, FG ;
KASTAN, MB ;
LIEBERMAN, MW .
BIOCHEMISTRY, 1985, 24 (06) :1424-1428
[2]  
BIRD A, 1985, CELL, V40, P91, DOI 10.1016/0092-8674(85)90312-5
[3]   CPG-RICH ISLANDS AND THE FUNCTION OF DNA METHYLATION [J].
BIRD, AP .
NATURE, 1986, 321 (6067) :209-213
[4]   POSITION EFFECT VARIEGATION IN MOUSE [J].
CATTANACH, BM .
GENETICS RESEARCH, 1974, 23 (03) :291-+
[5]   DNA METHYLATION AND CPG SUPPRESSION [J].
COOPER, DN ;
GERBERHUBER, S .
CELL DIFFERENTIATION, 1985, 17 (03) :199-205
[6]   DNA METHYLATION IN NORMAL AND SV40-TRANSFORMED HUMAN-FIBROBLASTS [J].
DIALA, ES ;
PLENT, MM ;
COALSON, DW ;
HOFFMAN, RM .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1981, 102 (04) :1379-1384
[7]   DNA METHYLATION AND GENE ACTIVITY [J].
DOERFLER, W .
ANNUAL REVIEW OF BIOCHEMISTRY, 1983, 52 :93-124
[8]   INTEGRATION OF NEW ENDOGENOUS MOUSE MAMMARY-TUMOR VIRUS PROVIRAL DNA AT COMMON SITES IN THE DNA OF MAMMARY-TUMORS OF C3HF MICE AND HYPOMETHYLATION OF THE ENDOGENOUS MOUSE MAMMARY-TUMOR VIRUS PROVIRAL DNA IN C3HF MAMMARY-TUMORS AND SPLEENS [J].
ETKIND, PR ;
SARKAR, NH .
JOURNAL OF VIROLOGY, 1983, 45 (01) :114-123
[9]   THE INVITRO LIFE-SPAN OF MRC-5 CELLS IS SHORTENED BY 5-AZACYTIDINE-INDUCED DEMETHYLATION [J].
FAIRWEATHER, DS ;
FOX, M ;
MARGISON, GP .
EXPERIMENTAL CELL RESEARCH, 1987, 168 (01) :153-159
[10]   HYPOMETHYLATION DISTINGUISHES GENES OF SOME HUMAN CANCERS FROM THEIR NORMAL COUNTERPARTS [J].
FEINBERG, AP ;
VOGELSTEIN, B .
NATURE, 1983, 301 (5895) :89-92
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