HOX GENE ACTIVATION BY RETINOIC ACID

被引：204

作者：

BONCINELLI, E ^{[1
]}

SIMEONE, A ^{[1
]}

ACAMPORA, D ^{[1
]}

MAVILIO, F ^{[1
]}

机构：

[1] IST SCI HS RAFFAELE,I-20132 MILAN,ITALY

来源：

TRENDS IN GENETICS | 1991年 / 7卷 / 10期

关键词：

D O I：

10.1016/0168-9525(91)90423-N

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Vertebrate homeobox genes of the Hox family are, like Drosophila homeotic genes, organized in gene clusters and show a strict correspondence, or collinearity, between the order of the genes (3' to 5') within the chromosomal cluster and that of their expression domains (anterior to posterior) in the embryo. Recent data obtained from embryonal carcinoma cells induced to differentiate by retinoic acid cast some light on the molecular mechanisms underlying the collinear expression of the Hox genes.

引用

收藏

页码：329 / 334

页数：6

相关论文

共 38 条

[1] THE HUMAN HOX GENE FAMILY [J].

ACAMPORA, D ;

DESPOSITO, M ;

FAIELLA, A ;

PANNESE, M ;

MIGLIACCIO, E ;

MORELLI, F ;

STORNAIUOLO, A ;

NIGRO, V ;

SIMEONE, A ;

BONCINELLI, E .

NUCLEIC ACIDS RESEARCH, 1989, 17 (24) :10385-10402

[2] HOX AND HOM - HOMOLOGOUS GENE CLUSTERS IN INSECTS AND VERTEBRATES [J].

AKAM, M .

CELL, 1989, 57 (03) :347-349

[3] DEVELOPMENTAL BIOLOGY - WONDROUS TRANSFORMATION [J].

AKAM, M .

NATURE, 1991, 349 (6307) :282-282

[4] A MURINE EVEN-SKIPPED HOMOLOG, EVX-1, IS EXPRESSED DURING EARLY EMBRYOGENESIS AND NEUROGENESIS IN A BIPHASIC MANNER [J].

BASTIAN, H ;

GRUSS, P .

EMBO JOURNAL, 1990, 9 (06) :1839-1852

[5] EVIDENCE FOR POSITIVE AND NEGATIVE REGULATION OF THE HOX-3.1 GENE [J].

BIEBERICH, CJ ;

UTSET, MF ;

AWGULEWITSCH, A ;

RUDDLE, FH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (21) :8462-8466

[6] DEVELOPMENTAL BIOLOGY - WE MAY NOT HAVE A MORPHOGEN [J].

BROCKES, J .

NATURE, 1991, 350 (6313) :15-15

[7] RETINOIDS, HOMEOBOX GENES, AND LIMB MORPHOGENESIS [J].

BROCKES, JP .

NEURON, 1989, 2 (04) :1285-1294

[8] DIFFERENTIAL UTILIZATION OF THE SAME READING FRAME IN A XENOPUS HOMEOBOX GENE ENCODES 2 RELATED PROTEINS SHARING THE SAME DNA-BINDING SPECIFICITY [J].

CHO, KWY ;

GOETZ, J ;

WRIGHT, CVE ;

FRITZ, A ;

HARDWICKE, J ;

DEROBERTIS, EM .

EMBO JOURNAL, 1988, 7 (07) :2139-2149

[9] STRUCTURAL-ANALYSIS OF MURINE GENES CONTAINING HOMOEO BOX SEQUENCES AND THEIR EXPRESSION IN EMBRYONAL CARCINOMA-CELLS [J].

COLBERGPOLEY, AM ;

VOSS, SD ;

CHOWDHURY, K ;

GRUSS, P .

NATURE, 1985, 314 (6013) :713-718

[10] EVX2, A HUMAN HOMEOBOX GENE HOMOLOGOUS TO THE EVEN-SKIPPED SEGMENTATION GENE, IS LOCALIZED AT THE 5' END OF HOX4 LOCUS ON CHROMOSOME-2 [J].

DESPOSITO, M ;

MORELLI, F ;

ACAMPORA, D ;

MIGLIACCIO, E ;

SIMEONE, A ;

BONCINELLI, E .

GENOMICS, 1991, 10 (01) :43-50

← 1 2 3 4 →