SYNTHESIS OF (2S,5S)-2,5-BIS(PHENYLMETHYL)-1,4-DIAZABICYCLO[2.2.2]OCTANE

被引：7

作者：

SOAI, K

OSHIO, A

YONEYAMA, H

机构：

[1] Department of Applied Chemistry, Faculty of Science, Science University of Tokyo, Shinjuku, Tokyo

来源：

TETRAHEDRON-ASYMMETRY | 1992年 / 3卷 / 03期

关键词：

D O I：

10.1016/S0957-4166(00)80274-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

(2S,5S)-2,5-Bis(phenylmethyl)-1,4-diazabicyclo [2.2.2]octane [(2S,5S)-bis(phenylmethyl)-DABCO] (6), a potentially useful chiral catalyst for asymmetric syntheses, was synthesized from a chiral piperazine.

引用

页码：359 / 360

页数：2

共 9 条

[1] SYNTHETIC POTENTIAL OF THE TERTIARY-AMINE-CATALYSED REACTION OF ACTIVATED VINYL CARBANIONS WITH ALDEHYDES [J].

DREWES, SE ;

ROOS, GHP .

TETRAHEDRON, 1988, 44 (15) :4653-4670

[2] REACTIONS OF HYDROXYL-GROUPS WITH "TOSYLCHLORIDE-DIMETHYLAMINOPYRIDINE SYSTEM - DIRECT SYNTHESIS OF CHLORIDES FROM HYDROXYCOMPOUNDS [J].

HWANG, CK ;

LI, WS ;

NICOLAOU, KC .

TETRAHEDRON LETTERS, 1984, 25 (22) :2295-2296

[3] ASYMMETRIC-SYNTHESIS USING CHIRAL PIPERAZINES .3. ENANTIOSELECTIVE ADDITION OF DIALKYLZINCS TO ARYL ALDEHYDES CATALYZED BY CHIRAL PIPERAZINES [J].

NIWA, S ;

SOAI, K .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1991, (11) :2717-2720

[4] FACILE SYNTHESIS OF ENANTIOPURE TRANS-2,3-DIPHENYL-1,4-DIAZABICYCLO[2.2.2]OCTANE [J].

OI, R ;

SHARPLESS, KB .

TETRAHEDRON LETTERS, 1991, 32 (37) :4853-4854

[5]

OISHI T, 1991, 61ST NAT M CHEM SOC

[6] SYNTHESIS OF (2S, 5S)-2, 5-BIS(PHENYLMETHYL)PIPERAZINE BY THE REDUCTION WITH SODIUM-BOROHYDRIDE USING TITANIUM TETRACHLORIDE [J].

SOAI, K ;

HAYASHI, H ;

HASEGAWA, H .

HETEROCYCLES, 1986, 24 (05) :1287-1289

[7] CHIRAL PIPERAZINE AS A NEW CHIRAL CATALYST FOR THE ENANTIOSELECTIVE ADDITION OF DIALKYL ZINCS TO ARYL ALDEHYDES [J].

SOAI, K ;

NIWA, S ;

YAMADA, Y ;

INOUE, H .

TETRAHEDRON LETTERS, 1987, 28 (41) :4841-4842

[8] THE PREPARATION OF N-PROTECTED AMINO-ALCOHOLS AND N-PROTECTED PEPTIDE ALCOHOL BY REDUCTION OF THE CORRESPONDING ESTERS WITH SODIUM-BOROHYDRIDE - AN IMPROVED PROCEDURE INVOLVING A SLOW ADDITION OF A SMALL AMOUNT OF METHANOL [J].

SOAI, K ;

OYAMADA, H ;

TAKASE, M .

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1984, 57 (08) :2327-2328

[9] PRACTICAL PROCEDURE FOR THE CHEMOSELECTIVE REDUCTION OF ESTERS BY SODIUM-BOROHYDRIDE - EFFECT OF THE SLOW ADDITION OF METHANOL [J].

SOAI, K ;

OYAMADA, H ;

TAKASE, M ;

OOKAWA, A .

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1984, 57 (07) :1948-1953

← 1 →