ANALGESIA IN TONSILLECTOMY - A DOUBLE-BLIND-STUDY ON PREOPERATIVE AND POSTOPERATIVE TREATMENT WITH DICLOFENAC

被引:42
作者
NORDBLADH, I [1 ]
OHLANDER, B [1 ]
BJORKMAN, R [1 ]
机构
[1] SAHLGRENS UNIV HOSP, DEPT CLIN PHARMACOL, S-41345 GOTHENBURG, SWEDEN
关键词
TONSILLECTOMY; ANALGESIA; PREOPERATIVE AND POSTOPERATIVE TREATMENT; HEMORRHAGE; NSAIDS;
D O I
10.1111/j.1365-2273.1991.tb00973.x
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
The efficacy and tolerability of diclofenac suppositories given pre and/or post-operatively were investigated in a randomized double-blind study on 99 patients undergoing tonsillectomy. In one group, 50 mg diclofenac was given 1 h preoperatively, followed by 50 mg directly after the operation. In another group, diclofenac 100 mg was given only immediately post-operatively. A significantly lower consumption of rescue analgesics (paracetamol and/or pethidine) was found in the group treated preoperatively with diclofenac and the average time until first demand of rescue analgesics was significantly longer compared to the group given diclofenac post-operatively only. The tolerance was good and no serious bleeding complications occurred in either group. In the treatment of post-operative pain after tonsillectomy, the combination of pre and post-operative administration of diclofenac suppositories resulted in significantly lower consumption of rescue analgesics and is thus preferable to administration solely post-operatively.
引用
收藏
页码:554 / 558
页数:5
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