THE EFFECT OF N-METHYLPROTOPORPHYRIN AND SUCCINYL-ACETONE ON THE REGULATION OF HEME-BIOSYNTHESIS IN CHICKEN HEPATOCYTES IN CULTURE

被引：38
作者：
DEMATTEIS, F [1 ]
MARKS, GS [1 ]
机构：
[1] QUEENS UNIV,DEPT PHARMACOL & TOXICOL,KINGSTON K7L 3N6,ONTARIO,CANADA
来源：
FEBS LETTERS | 1983年 / 159卷 / 1-2期
关键词：
D O I：
10.1016/0014-5793(83)80430-X
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：127 / 131
页数：5
相关论文
共 33 条
[1]   EFFECTS OF ANTIHYPERTENSIVE DRUGS ON HEPATIC HEME BIOSYNTHESIS, AND EVALUATION OF FERROCHELATASE INHIBITORS TO SIMPLIFY TESTING OF DRUGS FOR HEME PATHWAY INDUCTION [J].
ANDERSON, KE .
BIOCHIMICA ET BIOPHYSICA ACTA, 1978, 543 (03) :313-327
[2]   INHIBITION OF FERROCHELATASE BY N-METHYLPROTOPORPHYRIN-IX IS NOT ACCOMPANIED BY DELTA-AMINOLEVULINIC-ACID SYNTHETASE INDUCTION IN CHICK-EMBRYO LIVER-CELL CULTURE [J].
COLE, SPC ;
MARKS, GS ;
DEMONTELLANO, PRO ;
KUNZE, KL .
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1982, 60 (02) :212-215
[3]   DRUG-INDUCED PORPHYRIN BIOSYNTHESIS .19. POTENTIATION OF THE PORPHYRIN-INDUCING EFFECTS OF SKF 525-A IN THE CHICK-EMBRYO LIVER BY 3,5-DIETHOXYCARBONYL-1,4-DIHYDRO-2,4,6-TRIMETHYLPYRIDINE, AN INHIBITOR OF FERROCHELATASE [J].
COLE, SPC ;
VAVASOUR, EJ ;
MARKS, GS .
BIOCHEMICAL PHARMACOLOGY, 1979, 28 (24) :3533-3538
[4]   STIMULATION OF LIVER 5-AMINOLEVULINATE SYNTHETASE BY DRUGS AND ITS RELEVANCE TO DRUG-INDUCED ACCUMULATION OF CYTOCHROME-P-450 - STUDIES WITH PHENYLBUTAZONE AND 3,5-DIETHOXYCARBONYL-1,4-DIHYDROCOLLIDINE [J].
DEMATTEIS, F ;
GIBBS, A .
BIOCHEMICAL JOURNAL, 1972, 126 (05) :1149-+
[5]   LIVER PRODUCTION OF N-ALKYLATED PORPHYRINS CAUSED IN MICE BY TREATMENT WITH SUBSTITUTED DIHYDROPYRIDINES - EVIDENCE THAT THE ALKYL GROUP ON THE PYRROLE NITROGEN ATOM ORIGINATES FROM THE DRUG [J].
DEMATTEIS, F ;
GIBBS, AH ;
FARMER, PB ;
LAMB, JH .
FEBS LETTERS, 1981, 129 (02) :328-331
[6]  
DEMATTEIS F, 1980, BIOCHEM J, V188, P145, DOI 10.1042/bj1880145
[7]   DRUG INTERACTIONS IN EXPERIMENTAL HEPATIC PORPHYRIA - MODEL FOR EXACERBATION BY DRUGS OF HUMAN VARIEGATE PORPHYRIA [J].
DEMATTEIS, F .
ENZYME, 1973, 16 (1-6) :266-275
[8]  
DEMATTEIS F, 1980, BIOCHEM J, V189, P645, DOI 10.1042/bj1890645
[9]   STRUCTURAL ISOMERISM AND CHIRALITY OF N-MONOSUBSTITUTED PROTOPORPHYRINS - POSSIBLE RELEVANCE TO BINDING OF N-METHYL PROTOPORPHYRIN BY FERROCHELATASE AND TO ORIENTATION OF HEME IN CYTOCHROME-P450 [J].
DEMATTEIS, F ;
JACKSON, AH ;
GIBBS, AH ;
RAO, KRN ;
ATTON, J ;
WEERASINGHE, S ;
HOLLANDS, C .
FEBS LETTERS, 1982, 142 (01) :44-48
[10]   CONVERSION OF LIVER HEME INTO N-SUBSTITUTED PORPHYRINS OR GREEN PIGMENTS [J].
DEMATTEIS, F ;
GIBBS, AH ;
JACKSON, AH ;
WEERASINGHE, S .
FEBS LETTERS, 1980, 119 (01) :109-112
1234