RESTRICTION FRAGMENT LENGTH POLYMORPHISMS AT THE HUMAN PARATHYROID-HORMONE GENE LOCUS

被引：63
作者：
SCHMIDTKE, J
PAPE, B
KRENGEL, U
LANGENBECK, U
COOPER, DN
BREYEL, E
MAYER, H
机构：
[1] UNIV GOTTINGEN, INST HUMAN GENET, D-3400 GOTTINGEN, FED REP GER
[2] GESELL BIOTECHNOL FORSCH MBH, D-3300 BRUNSWICK, FED REP GER
来源：
HUMAN GENETICS | 1984年 / 67卷 / 04期
关键词：
D O I：
10.1007/BF00291404
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Two common Pst I and Taq I restriction enzyme fragment length polymorphisms (RFLP) were detected at the human parathyroid hormone (PTH) gene locus. The allele frequencies in a Northern German population were 0.578/0.422 (Pst I) and 0.628/0.372 (Taq I). The allele distributions follow Hardy-Weinberg expectations of equilibrium in the population. The Mendelian nature of the polymorphisms were confirmed in family studies.
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页码：428 / 431
页数：4
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