A 75-year-old man presented with a right cerebellopontine angle tumor 11 months after complete macroscopic resection of a right acoustic neurilemoma. Histological examination of the recurrent tumor showed a malignant spindle-cell neoplasm with positive staining for S-100 protein. The patient has no stigmata of von Recklinghausen's disease. It is proposed that this recurrence represents progression from a benign to a malignant acoustic nerve-sheath tumor, an event that is extremely rare outside the clinicopathological context of neurofibromatosis.
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China Med Univ, Affiliated Hosp 1, Dept Gen Surg, Shenyang, Peoples R ChinaChina Med Univ, Affiliated Hosp 1, Dept Gen Surg, Shenyang, Peoples R China
Liu, Ting-ting
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Han, Yang
Zheng, Song
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China Med Univ, Affiliated Hosp 1, Dept Dermatol & STD, Shenyang, Peoples R ChinaChina Med Univ, Affiliated Hosp 1, Dept Gen Surg, Shenyang, Peoples R China
Zheng, Song
Li, Bo
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China Med Univ, Affiliated Hosp 1, Dept Dermatol & STD, Shenyang, Peoples R ChinaChina Med Univ, Affiliated Hosp 1, Dept Gen Surg, Shenyang, Peoples R China
Li, Bo
Liu, Yu-qi
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China Med Univ, Grad Sch, Shenyang, Peoples R ChinaChina Med Univ, Affiliated Hosp 1, Dept Gen Surg, Shenyang, Peoples R China
Liu, Yu-qi
Chen, Yi-xian
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China Med Univ, Grad Sch, Shenyang, Peoples R ChinaChina Med Univ, Affiliated Hosp 1, Dept Gen Surg, Shenyang, Peoples R China
Chen, Yi-xian
Liu, Yong-feng
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China Med Univ, Affiliated Hosp 1, Dept Gen Surg, Shenyang, Peoples R ChinaChina Med Univ, Affiliated Hosp 1, Dept Gen Surg, Shenyang, Peoples R China
Liu, Yong-feng
Wang, En-hua
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China Med Univ, Affiliated Hosp 1, Dept Pathol, Shenyang, Peoples R ChinaChina Med Univ, Affiliated Hosp 1, Dept Gen Surg, Shenyang, Peoples R China