STUDIES ON THE MECHANISM OF INDUCTION OF MICROSOMAL CYTOCHROME-P452 AND PEROXISOMAL BIFUNCTIONAL ENZYME MESSENGER-RNAS BY NAFENOPIN IN PRIMARY CULTURES OF ADULT-RAT HEPATOCYTES

被引：7
作者：
BIERI, F
MEIER, V
STAUBLI, W
MUAKKASSAHKELLY, SF
WAECHTER, F
SAGELSDORFF, P
BENTLEY, P
机构：
来源：
BIOCHEMICAL PHARMACOLOGY | 1991年 / 41卷 / 02期
关键词：
D O I：
10.1016/0006-2952(91)90493-O
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
[No abstract available]
引用
收藏
页码：310 / 312
页数：3
相关论文
共 18 条
[1]   INCREASED PEROXISOMAL ENZYME MESSENGER-RNA LEVELS IN ADULT-RAT HEPATOCYTES CULTURED IN A CHEMICALLY DEFINED MEDIUM AND TREATED WITH NAFENOPIN [J].
BIERI, F ;
NEMALI, MR ;
MUAKKASSAHKELLY, S ;
WAECHTER, F ;
STAUBLI, W ;
REDDY, JK ;
BENTLEY, P .
TOXICOLOGY IN VITRO, 1988, 2 (04) :235-&
[2]   STIMULATION OF DNA-SYNTHESIS BUT NOT OF PEROXISOMAL BETA-OXIDATION BY NAFENOPIN IN PRIMARY CULTURES OF MARMOSET HEPATOCYTES [J].
BIERI, F ;
STAUBLI, W ;
WAECHTER, F ;
MUAKKASSAHKELLY, S ;
BENTLEY, P .
CELL BIOLOGY INTERNATIONAL REPORTS, 1988, 12 (12) :1077-1087
[3]   USE OF PRIMARY CULTURES OF ADULT-RAT HEPATOCYTES TO INVESTIGATE MECHANISMS OF ACTION OF NAFENOPIN, A HEPATOCARCINOGENIC PEROXISOME PROLIFERATOR [J].
BIERI, F ;
BENTLEY, P ;
WAECHTER, F ;
STAUBLI, W .
CARCINOGENESIS, 1984, 5 (08) :1033-1039
[4]   REGULATION OF MAMMALIAN PROTEIN-SYNTHESIS INVIVO - STIMULATED LIVER RIBONUCLEIC-ACID SYNTHESIS INVIVO AFTER CYCLOHEXIMIDE TREATMENT [J].
CHIH, JJ ;
PIKE, LM ;
DEVLIN, TM .
BIOCHEMICAL JOURNAL, 1977, 168 (01) :57-63
[5]   PEROXISOME PROLIFERATION DUE TO DI(2-ETHYLHEXYL) PHTHALATE (DEHP) - SPECIES-DIFFERENCES AND POSSIBLE MECHANISMS [J].
ELCOMBE, CR ;
MITCHELL, AM .
ENVIRONMENTAL HEALTH PERSPECTIVES, 1986, 70 :211-219
[6]   INDUCIBILITY OF RAT-LIVER CYTOCHROME-P-450IA1 (P-450C) MESSENGER-RNA DURING THE PARTIAL INHIBITION OF PROTEIN-SYNTHESIS [J].
FOLDES, RL ;
BRESNICK, E .
BIOCHEMICAL PHARMACOLOGY, 1989, 38 (06) :1017-1019
[7]   PEROXISOME PROLIFERATION IN PRIMARY CULTURES OF RAT HEPATOCYTES [J].
GRAY, TJB ;
LAKE, BG ;
BEAMAND, JA ;
FOSTER, JR ;
GANGOLLI, SD .
TOXICOLOGY AND APPLIED PHARMACOLOGY, 1983, 67 (01) :15-25
[8]   THE EFFECT OF PEROXISOME PROLIFERATORS ON MICROSOMAL, PEROXISOMAL, AND MITOCHONDRIAL ENZYME-ACTIVITIES IN THE LIVER AND KIDNEY [J].
HAWKINS, JM ;
JONES, WE ;
BONNER, FW ;
GIBSON, GG .
DRUG METABOLISM REVIEWS, 1987, 18 (04) :441-515
[9]   THE EFFECT OF BEZAFIBRATE AND LONG-CHAIN FATTY-ACIDS ON PEROXISOMAL ACTIVITIES IN CULTURED RAT HEPATOCYTES [J].
HERTZ, R ;
ARNON, J ;
BARTANA, J .
BIOCHIMICA ET BIOPHYSICA ACTA, 1985, 836 (02) :192-200
[10]  
ISRAEL DI, 1985, J BIOL CHEM, V260, P5648
12