TRANSCELLULAR TRANSACTIVATION BY THE HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 TAT PROTEIN

被引：112

作者：

HELLAND, DE ^{[1
]}

WELLES, JL ^{[1
]}

CAPUTO, A ^{[1
]}

HASELTINE, WA ^{[1
]}

机构：

[1] HARVARD UNIV,SCH MED,DANA FARBER CANC INST,DIV HUMAN RETROVIROL,44 BINNEY ST,BOSTON,MA 02115

来源：

JOURNAL OF VIROLOGY | 1991年 / 65卷 / 08期

关键词：

D O I：

10.1128/JVI.65.8.4547-4549.1991

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The human immunodeficiency virus type 1 (HIV-1) transactivator (tat) protein produced in one cell activated HIV-1 promoter-directed gene expression in a second cell, provided the cells were in direct contact with one another. This observation suggests that the tat protein produced in HIV-1-infected cells has a physiological effect on neighboring cells.

引用

页码：4547 / 4549

页数：3

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