IDENTIFICATION OF THE CALCIUM-BINDING PROTEIN CALGRANULIN IN THE MATRIX OF STRUVITE STONES

被引：11

作者：

BENNETT, J ^{[1
]}

DRETLER, SP ^{[1
]}

SELENGUT, J ^{[1
]}

ORMEJOHNSON, WH ^{[1
]}

机构：

[1] MIT,DEPT CHEM,CAMBRIDGE,MA 02139

来源：

JOURNAL OF ENDOUROLOGY | 1994年 / 8卷 / 02期

关键词：

D O I：

10.1089/end.1994.8.95

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

The identification of calcium-binding proteins in urine and kidney stones has led to a closer look at the role of matrix proteins in urolithiasis. We analyzed five struvite stones for protein content and identified two bands (8 and 14 KDa) that were confirmed by gel electrophoresis and amino acid sequencing to be calgranulin. This protein, which is known by several other names, has bacteriostatic antifungal activity. Its role in the formation of struvite stones warrants further investigation.

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页码：95 / 98

页数：4

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