RESPONSE TO INTRAVENOUS LIDOCAINE INFUSION DIFFERS BASED ON CLINICAL-DIAGNOSIS AND SITE OF NERVOUS-SYSTEM INJURY

被引：79
作者：
GALER, BS
MILLER, KV
ROWBOTHAM, MC
机构：
[1] UNIV CALIF SAN FRANCISCO,DEPT NEUROL,SAN FRANCISCO,CA 94143
[2] UNIV CALIF SAN FRANCISCO,DEPT ANESTHESIA,SAN FRANCISCO,CA 94143
来源：
NEUROLOGY | 1993年 / 43卷 / 06期
关键词：
D O I：
10.1212/WNL.43.6.1233
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
We analyzed retrospectively pain relief from an intravenous lidocaine infusion (5 mg/kg/hr for 60 to 90 minutes) in 111 patients with chronic nonmalignant pain. Patients with peripheral nervous system (PNS) injury reported substantially more pain relief than those with central nervous system (CNS) injury or with pain of unknown etiology. These findings suggest that (1) the pathophysiology of chronic pain due to PNS injury is different from that due to CNS injury and idiopathic pain, and that (2) pain due to PNS damage may be suppressible by local anesthetic antiarrhythmic agents.
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页码：1233 / 1235
页数：3
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